NFL Week 2: Odds, lines, spreads and best bets | NFL and NCAA Betting Picks

NFL Week 2: Odds, lines, spreads and best bets | NFL and NCAA Betting Picks

• After a Week 1 that included five game-winning touchdowns in the final two minutes of regulation or overtime, Week 2 kicks off Thursday with an AFC clash between Justin Herbert’s Chargers and Patrick Mahomes’ Chiefs and concludes with a Monday-night doubleheader with the Titans in Buffalo before the Vikings visit Philadelphia.

• Mahomes tossed five touchdowns for the sixth time in his career, as the Chiefs dismantled Arizona, 44-21. Herbert threw for three scores, and new OLB Khalil Mack recorded three sacks and a forced fumble against his former team, the Raiders, in a 24-19 Chargers win.

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Estimated reading time: 3 min


Here are Week 2 early lines, courtesy of BetMGM. Our best early looks are coming shortly.

Thursday, Sept. 15

Los Angeles Chargers @ Kansas City Chiefs

Spread Total Moneyline
Chargers +3 (-105) Y 54 (-110) +145
Chiefs -3 (-105) U 54 (-110 -175

Sunday, Sept. 18

Miami Dolphins @ Baltimore Ravens

Spread Total Moneyline
Dolphins +3.5 (-115) Y 45.5 (-110) +150
Ravens -3.5 (-105) U 45.5 (-110) -185

New York Jets @ Cleveland Browns

Spread Total Moneyline
Jets +6 (-110) Y 42.5 (-110) +220
browns -6 (-110) U 42.5 (-110) -275

Washington Commanders @ Detroit Lions

Spread Total Moneyline
Commanders +1.5 (-105) Y 46.5 (-110) +110
lions -1.5 (-115) U 46.5 (-110) -135

Indianapolis Colts @ Jacksonville Jaguars

Spread Total Moneyline
Colts -4.5 (-110) Y 45.5 (-115) -200
Jaguars +4.5 (-110) U 45.5 (-105) +170

Carolina Panthers @ New York Giants

Spread Total Moneyline
Panthers +2.5 (-110) Y 43.5 (-110) +110
Giants -2.5 (-110) U 43.5 (-110) -135

Atlanta Falcons @ Los Angeles Rams

Spread Total Moneyline
Falcons +10.5 (-115) O47.5(-115) +450
rams -10.5 (-105) U47.5(-115) -650

Seattle Seahawks @ San Francisco 49ers

Spread Total Moneyline
Seahawks +9.5 (-110) O42.5 (-105) +340
49ers -9.5 (-110) U42.5 (-115) -450

Houston Texans @ Denver Broncos

Spread Total Moneyline
Texas +10 (-110) O43.5 (-115) +340
Broncos -10 (-110) U43.5 (-105) -450

New England Patriots @ Pittsburgh Steelers

Spread Total Moneyline
Patriots TBA TBA TBA
Steelers TBA TBA TBA

Arizona Cardinals @ Las Vegas Raiders

Spread Total Moneyline
Cardinals +3.5 (-110) O51.5 (-110) +155
Raiders -3.5 (-110) U51.5 (-110) -165

Chicago Bears @ Green Bay Packers

Spread Total Moneyline
Bears +9.5 (-110) O43.5 (-110) +325
Packers -9.5 (-110) U43.5 (-110) -400

Monday, Sept. 19

Tennessee Titans @ Buffalo Bills

Spread Total Moneyline
Titans +9.5 (-105) O49.5 (-115) +325
bills -9.5 (-115) U49.5 (-105) -400

Minnesota Vikings @ Philadelphia Eagles

Spread Total Moneyline
Titans +3 (-120) O49.5 (-110) +120
bills -3 (+100) U49.5 (-110) -145

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